Normalize methylation levels

# S4 method for DsNOMe
normalizeMeth(.object, type = "sites", method = "quantile", reaggregate = TRUE)

Arguments

.object

DsNOMe object

type

character string specifying a name for the region type (default: sites)

method

normalization method to be applied. Currently only 'quantile' is supported

reaggregate

redo region aggregation (only has an effect if type is sites and there are aggregated regions in the dataset)

Value

a new DsNOMe object with normalized methylation levels

Author

Fabian Mueller